Robert and Katherine Thorn are as loving of parents as any young boy could ask for, but as fate would have it, their new son Damien is far from the typical child. As the mysterious boy's growth begins to share frightening parallels with the Biblical passages detailing the rise of the Antichrist, and the lives of all who seek to reveal his true nature are cut gruesomely short, Robert and Katherine are forced to face the horrifying prospect that their child has been sent from Satan to hasten the fall of modern civilization, and that there is little they can do to curb his prophesied path of ultimate destruction.