Has Spidey finally met a superior foe? Spider-Man is grief-stricken after a shocking death - but there's no shortage of super villains lining up to put him in the grave, as well! First up: a revitalized and upgraded Doctor Octopus! As Otto takes his deadlier-than-ever tentacles on a rampage through Oscorp, can Spidey clean Doc Ock's clock? With his back against the wall, perhaps a surprising ally can swing things in the wall-crawler's favor! Then, wedding bells are ringing, and Peter Parker has to make it to the church on time - because he's the best man! Janice Lincoln and Randy Robertson are tying the knot, and there's no way that all the crime bosses in NYC aren't seeing this as an opportunity to knock off the father of the bride: the whispering menace Tombstone!